Coronaviruses are a group of viruses that cause diseases in mammals (including bats) and birds. In humans, coronaviruses cause respiratory tract infections that are typically mild, such as the common cold, but rarer forms such as SARS, MERS, and COVID-19 can be lethal.
The name coronavirus is derived from the Latin corona, meaning “crown” or “halo”, which refers to the virus particles (virions) having a fringe reminiscent of a crown or of a solar corona.
According to the CDC, in rare cases, animal coronaviruses can infect people and then spread between people. Three examples are MERS-CoV, SARS-CoV, and a new coronavirus, named SARS-CoV-2. The disease caused by SARS-CoV-2 is named “coronavirus disease 2019” (abbreviated “COVID-19”).
All three of these animal-to-people coronaviruses have their origins in bats. Many of the earliest patients at the epicenter of the outbreak in Wuhan, Hubei Province, China had some link to a large seafood and live animal market, suggesting animal-to-person spread, which then became person-to-person.
As of yesterday, March 2, 2020, the CDC says in the United States there are 43 confirmed cases of COVID-19; 17 hospitalized; 2 deaths; and 10 states reporting cases (Arizona, California, Florida, Illinois, Massachusetts, New York, Oregon, Rhode Island, Washington, Wisconsin).
James Robb, M.D., F.C.A.P. (Fellow of the College of American Pathologists), is a consulting pathologist to the National Cancer Institute (NCI) and the Office of Biorepositories and Biospecimen Research (OBBR), and is also the Leader of the cancer Human Biobank (caHUB) Biospecimens Subgroup, Latin America Cancer Research Network (LACRN) Pathology Committee, and National Community Cancer Centers Biospecimens (NCCCP) Pillar. He also serves on the Board of Governors of the College of American Pathologists (CAP). Dr. Robb’s research interests include molecular oncologic and neurotropic virology.
In other words, Dr. Robb is a virologist — a molecular biologist who specializes in virology, the study of viruses and viral diseases. The coronavirus (COVID-19) is a virus. More than that, Dr. Robb was one of the first molecular virologists in the world to work on coronaviruses in the 1970s.
Below is an email from Dr. Robb on the coronavirus precautions we should take (source: Eat This, Not That!, among many other websites):
When I was a professor of pathology at the University of California San Diego, I was one of the first molecular virologists in the world to work on coronaviruses (the 1970s). I was the first to demonstrate the number of genes the virus contained. Since then, I have kept up with the coronavirus field and its multiple clinical transfers into the human population (e.g., SARS, MERS), from different animal sources.
The current projections for its expansion in the US are only probable, due to continued insufficient worldwide data, but it is most likely to be widespread in the US by mid to late March and April. Here is what I have done and the precautions that I take and will take. These are the same precautions I currently use during our influenza seasons, except for the mask and gloves.
(1) No Handshaking: Use a fist bump, slight bow, elbow bump, etc.
(2) Use only your knuckle: …to touch light switches. elevator buttons, etc.. Lift the gasoline dispenser with a paper towel or use a disposable glove.
(3) Open doors with your closed fist or hip: Do not grasp the handle with your hand, unless there is no other way to open the door. Especially important on bathroom and post office/commercial doors.
(4) Use disinfectant wipes: …at the stores when they are available, including wiping the handle and child seat in grocery carts.
(5) Wash your hands with soap: …for 10-20 seconds and/or use a greater than 60% alcohol-based hand sanitizer whenever you return home from any activity that involves locations where other people have been.
(6) Keep a bottle of hand sanitizer: …available at each of your home’s entrances. And in your car for use after getting gas or touching other contaminated objects when you can’t immediately wash your hands.
(7) Cough or sneeze into a disposable tissue: …and discard. Use your elbow only if you have to. The clothing on your elbow will contain an infectious virus that can be passed on for up to a week or more!
(8) Use latex or nitrile latex disposable gloves: …for use when going shopping, using the gasoline pump, and all other outside activity when you come in contact with contaminated areas. Note: This virus is spread in large droplets by coughing and sneezing. This means that the air will not infect you! But all the surfaces where these droplets land on are infectious for about a week on average—everything that is associated with infected people will be contaminated and potentially infectious. The virus is on surfaces and you will not be infected unless your unprotected face is directly coughed or sneezed upon. This virus only has cell receptors for lung cells (it only infects your lungs). The only way for the virus to infect you is through your nose or mouth via your hands or an infected cough or sneeze onto or into your nose or mouth.
(9) Stock up now on disposable surgical masks: …and use them to prevent you from touching your nose and/or mouth. (We touch our nose/mouth 90 times a day without knowing it!) This is the only way this virus can infect you—it is lung-specific. The mask will not prevent the virus in a direct sneeze from getting into your nose or mouth—it is only to keep you from touching your nose or mouth.
(10) Stock up now on hand sanitzers: …and latex/nitrile gloves (get the appropriate sizes for your family). The hand sanitizers must be alcohol-based and greater than 60% alcohol to be effective.
(11) Stock up now with zinc lozenges: These lozenges have been proven to be effective in blocking coronavirus (and most other viruses) from multiplying in your throat and nasopharynx. Use as directed several times each day when you begin to feel any “cold-like” symptoms beginning. It is best to lie down and let the lozenge dissolve in the back of your throat and nasopharynx. Cold-Eeze lozenges is one brand available, but there are other brands available.
A final word: I, as many others do, hope that this pandemic will be reasonably contained, but I personally do not think it will be. Humans have never seen this snake-associated virus before and have no internal defense against it. Tremendous worldwide efforts are being made to understand the molecular and clinical virology of this virus. Unbelievable molecular knowledge about the genomics, structure, and virulence of this virus has already been achieved. But there will be no drugs or vaccines available this year to protect us or limit the infection within us. Only symptomatic support is available.
I hope these personal thoughts will be helpful during this potentially catastrophic pandemic. Good luck to all of us!
Click here for the CDC’s very useful Q&A on coronavirus and COVID-19.
H/t FOTM reader patrioticgofer
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