Click on the embedded links for more on each disease.
(1) Alzheimer’s Disease:
Alzheimer’s, a type of senile dementia, affects your thinking, judgment, memory, and decision-making. It can make you feel confused and change how you act. Early on, you may be anxious or more easily annoyed. Over time, it can have more serious effects on your personality: A sweet, thoughtful person might become bossy and demanding, whereas someone who used to worry a lot or get stressed easily might become easygoing and content.
After Alzheimer’s, this is the next most common type of dementia. Clumps of unusual proteins, called Lewy bodies, form in the areas of your brain that control memory, movement, and thinking, thereby affecting you both mentally and physically. People who have it tend to become more passive, show little emotion, and lose interest in hobbies and other activities.
(3) Parkinson’s Disease:
While it might start as a little shakiness in your hand, Parkinson’s can eventually affect how you walk, talk, sleep, and think. Even early on, it can lead to things like obsessing over small details or a sudden carelessness. Later, you may seem absent-minded or not as social as you used to be. And it gets harder to keep your thoughts going in one direction.
(4) Huntington’s Disease:
This is an illness you’re born with, but it usually shows up in your 30s or 40s. It damages brain cells and affects every part of your life. You might have a hard time thinking clearly, or get angry to the point of hitting walls, or ignore basic things like brushing your teeth. And you may not even be aware it’s happening.
(5) Multiple Sclerosis (MS):
With this condition, your immune system attacks the nerves in your brain and spine. It can cause problems ranging from bladder issues to not being able to walk. In some cases, it can lead to a feeling of euphoria, where your happines is beyond normal and out of touch with reality. It can also bring on laughing or crying that seems out of control or not in line with how you really feel.
(7) Brain Tumor:
A tumor in your brain’s frontal lobe can affect the areas that handle personality, emotions, problem-solving, and memory. That can make you feel confused or forgetful. It can also cause mood swings, make you more aggressive, or trigger paranoid thoughts, like thinking people are “out to get you” when they’re not.
(8) Some Types of Cancer:
Tumors in the brain, spinal cord, and pituitary gland (which controls your hormone levels) can affect personality. So can adenocarcinoma, a type of cancerous tumor in cells that make mucus and other fluids which can occur in several parts of the body, including the breasts, colon, lungs, and pancreas.
When blood flow to part of your brain gets cut off, the cells there don’t get enough oxygen and start to die. The effects depend on how long the stroke lasts and where in the brain it happens, which is why you need to get help ASAP. You might not be able to move some parts of your body, and it can change your personality in some ways. You might lose your patience more easily, have serious mood swings, or act more impulsively than you did before.
(10) Traumatic Brain Injury:
After a serious blow to the head, changes in personality can be a hidden symptom that happens over time. In more serious cases, you may seem like a different person, saying or doing things you never would have in the past.
As it comes on, this reaches into every part of your life. It not only affects your mood, but also the kinds of things you think about, your memory, and how you make decisions. It changes how you think about the world around you. It can be very different in men and women: Women often feel worthless, sad, and guilty, while men tend to feel tired, irritated, and angry.
(12) Obsessive-compulsive Disorder (OCD):
OCD makes you feel anxious and have thoughts and urges you just can’t stop. For example, you might wash your hands over and over again. You might doubt yourself a lot and take a long time to finish simple tasks. It can get worse if someone criticizes you, because that feeds your anxiety.
(13) Bipolar Disorder:
This causes mood changes that go way beyond the normal ups and downs of daily life. When you’re up, you might feel jumpy, talk really fast, and take big risks. When you’re down, you might be worried, have low energy, and feel worthless. And sometimes, you might feel a mix of both. These intense changes can mess with your sleep and energy, and make it hard to think clearly.
This serious mental illness can make you hear voices and see things that aren’t there. You might believe things that have no basis in reality. At first, you just might not be as social as normal. As it gets worse, it can be tough to keep your thoughts on track, making it hard to even talk to people. And you may act in ways that are way out of character, hard to predict, and out of control.