Diabetes and sugar put you at risk for Alzheimer's

Alzheimer’s disease is a severe form of dementia that affects an estimated 5.2 million Americans, according to 2013 statistics. Approximately 7.7 million new cases of dementia are identified every year—which amounts to one new case every four seconds.
One in nine seniors over the age of 65 has Alzheimer’s, and the disease is now thought to be the third leading cause of death in the U.S., right behind heart disease and cancer.
While you cannot change your age and family history, there are modifiable lifestyle factors you can control to reduce your risk for developing this horrible disease. Those factors include diet, physical activity, weight (obesity), cognitive activity, smoking (tobacco), and diabetes.
liberal smokers
Dr Laura Phipps, of Alzheimer’s Research UK, said: “There is a large body of evidence linking diabetes to an increased risk of dementia but the biological mechanisms underlying this link are not yet fully understood. Further investment in research is crucial.”
Now researchers have discovered the biological mechanisms underlying the link between diabetes and Alzheimer’s.
David Pilditch reports for the UK’s Express, May 6, 2015, that researchers at Washington University in St. Louis, Missouri, found that high levels of glucose (sugar) in the blood rapidly increases the amount of the toxic protein amyloid beta believed to be drive the complex changes in the brain which lead to Alzheimer’s.

Note: Plaques form when protein pieces called beta-amyloid clump together. Beta-amyloid comes from a larger protein found in the fatty membrane surrounding nerve cells. Beta-amyloid is chemically “sticky” and gradually builds up into plaques. The sticky protein forms harmful “plaques” that destroy the brain, killing off nerves and causing memory loss and confusion. Finding ways of preventing the plaques is seen as the key to wiping out Alzheimer’s.

Alzheimer's brain cells

Lead researcher Dr. Shannon Macauley said: “Our results suggest diabetes, or other conditions that make it hard to control blood sugar levels, can have harmful effects on brain function and exacerbate neurological conditions such as Alzheimer’s disease. The link we have discovered could lead us to future treatment targets that reduce these effects.”
People with diabetes cannot control the levels of glucose in their blood. In the latest study, published in The Journal of Clinical Investigation, mice bred to develop an Alzheimer’s-like condition were injected with glucose. In young mice without amyloid plaques, doubling glucose in the bloodstream increased the protein in the brain by 20%. In older mice, which already had these plaques, the amount of amyloid beta rose by 40%.
normal vs. Alzheimer's brain
A sensible diet; not getting fat; exercise; staying mentally active and engaged; don’t smoke; avoid sweets . . . .
Isn’t the above the age-old counsel we already know? And yet, we seem to have to rediscover and reconfirm that truth time and again . . . .

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5 years ago

We humans –contra our overly vaunted “intelligence”– are very self-destructive when we fail to develop equivalent spiritual-religious capacities. Yes, we have free will, but when it serves ONLY the rational part of our minds, then we get into TROUBLE!
For a full discussion of this see anything by Dr Joseph Chilton Pearce: https://www.ratical.org/many_worlds/JCP98.html

Doc's Wife
Doc's Wife
5 years ago

Doc and I have been mostly gluten-free (must have occasional pizza) for 3 years. With his large family history of Alzheimer’s, and after reading the book, “Wheat Belly”, we opted to go this route. Today’s wheat is very different from what is was in the past, and it is known to contribute to Alzheimer’s. A positive side effect of doing this is a flatter tummy and weight loss!

5 years ago

I have a friend who suffers from Alzheimer’s and since I am closely connected with her family, I have learned a lot about it. On her really bad days she seems to get better if they let her eat some sweets. I don’t know the reason for this since sugar is supposed to be bad for you. Probably this is an old wives’ tale, but I have heard all my life that if you eat white fleshed fruits and vegetables (turnip roots, cauliflower, white asparagus, pears, potatoes etc.) it will protect you from Alzheimer’s. .

Steven Broiles
5 years ago

Good article, but a couple of points: First, I am as conservative as the old-timers. I am NOT a Fox News conservative; I am closer to Barry Goldwater in my beliefs. (I said “closer” and not “identical.”) I am a conservative, and I smoke. And I will tell you, it is the WORST addiction of them all. (Some drug addicts have told me quitting tobacco is harder than quitting cocaine or heroin.) I am sorry I ever started smoking. With all the money I’ve blown on cigarettes over the past 31 years, I could have bought a small house in… Read more »

Steven Broiles
5 years ago
Reply to  Steven Broiles

Leonardo Dicaprio and many other Hollywood actors may be moral cretins, but at least they can act. (And at least Dicaprio doesn’t hang out with the Kardashians!)

Terry Gomez
4 years ago

I like your article so much, I’ll make sure to bookmark it and return to learn more of your useful info, thanks so much to the author for providing this knowledge!!
Diabetes is a chronic disease, but also a treatable disease, in milder cases, diabetes can be easily controlled by the perfect diet and exercise, while more serious cases, Diabetes is often treated with a combination of insulin, meds, exercise, and a special diabetic diet.